Gene information
Official symbol KCNN2
Official full name potassium calcium-activated channel subfamily N member 2
Gene type protein-coding gene
Chromosome5q22.3
Alias symbolKCa2.2; hSK2
Gene familyPotassium calcium-activated channels
Resources
Entrez Gene 3781
HGNC HGNC:6291
Ensembl ENSG00000080709
Vega OTTHUMG00000128836
UCSC uc003kqo.5
GO terms: 42 records
GO Description Category LogP Number of genes Detail
GO:0003012 muscle system process GO Biological Processes -27.3938503 63 More
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003015 heart process GO Biological Processes -12.3962712 26 More
GO:0005216 ion channel activity GO Molecular Functions -2.12987867 14 More
GO:0005227 calcium activated cation channel activity GO Molecular Functions -2.46582511 5 More
GO:0005242 inward rectifier potassium channel activity GO Molecular Functions -3.12309097 6 More
GO:0005244 voltage-gated ion channel activity GO Molecular Functions -1.48636532 7 More
GO:0005261 cation channel activity GO Molecular Functions -1.68739377 23 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008016 regulation of heart contraction GO Biological Processes -27.6827716 55 More
GO:0010959 regulation of metal ion transport GO Biological Processes -23.6318171 71 More
GO:0015267 channel activity GO Molecular Functions -2.12225487 15 More
GO:0015276 ligand-gated ion channel activity GO Molecular Functions -3.44721899 9 More
GO:0015318 inorganic molecular entity transmembrane transporter activity GO Molecular Functions -2.11605072 20 More
GO:0019904 protein domain specific binding GO Molecular Functions -3.48133193 23 More
GO:0022803 passive transmembrane transporter activity GO Molecular Functions -2.11455525 15 More
GO:0022832 voltage-gated channel activity GO Molecular Functions -1.48636532 7 More
GO:0022834 ligand-gated channel activity GO Molecular Functions -3.44721899 9 More
GO:0022836 gated channel activity GO Molecular Functions -2.68852033 13 More
GO:0022839 ion gated channel activity GO Molecular Functions -1.54957362 3 More
GO:0030029 actin filament-based process GO Biological Processes -9.62516039 61 More
GO:0030048 actin filament-based movement GO Biological Processes -8.41720734 20 More
GO:0030425 dendrite GO Cellular Components -4.55233052 48 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0042391 regulation of membrane potential GO Biological Processes -15.0641346 59 More
GO:0042803 protein homodimerization activity GO Molecular Functions -14.2815375 77 More
GO:0043025 neuronal cell body GO Cellular Components -9.18558636 52 More
GO:0043197 dendritic spine GO Cellular Components -2.33781374 8 More
GO:0043266 regulation of potassium ion transport GO Biological Processes -7.37974754 20 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0044297 cell body GO Cellular Components -11.7206640 62 More
GO:0044309 neuron spine GO Cellular Components -2.32281755 8 More
GO:0060047 heart contraction GO Biological Processes -8.83781505 20 More
GO:0060048 cardiac muscle contraction GO Biological Processes -7.88412825 17 More
GO:0070252 actin-mediated cell contraction GO Biological Processes -7.79385832 16 More
GO:0086002 cardiac muscle cell action potential involved in contraction GO Biological Processes -2.32404204 6 More
GO:0097447 dendritic tree GO Cellular Components -4.82959150 49 More
GO:0099094 ligand-gated cation channel activity GO Molecular Functions -2.10410515 6 More
GO:1903522 regulation of blood circulation GO Biological Processes -44.9821911 79 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa04911 Insulin secretion KEGG Pathway -2.01839081 5 More
Drug-Gene interaction
view
Related drugs: 1 record
Drug name Interaction type Source PMID View
dequalinium TTD view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
cg23615676 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
All rights reserved: Soochow University Center for Systems Biology